PROPERTIES OF THE IGNIMBRITES IN THE ARCHITECTURE OF THE HISTORICAL CENTER OF AREQUIPA, PERU


Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.

Abnormal processing of TAR DNA binding protein 43 (TDP-43) has been identified as a major factor in neuronal degeneration during amyotrophic lateral sclerosis (ALS) or frontotemporal lobar degeneration (FTLD).It is unclear how changes to TDP-43, including nuclear to cytosolic translocation and subsequent accumulation, are controlled in these diseas

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Neuromodulation for treatment-resistant depression: Functional network targets contributing to antidepressive outcomes

Non-invasive brain stimulation is designed to target accessible brain regions that underlie many psychiatric disorders.One such method, transcranial magnetic stimulation (TMS), is commonly used in patients with treatment-resistant depression (TRD).However, for non-responders, the choice of an alternative therapy is unclear and often decided empiric

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